Annual Report & Accounts 2011 - Notice of Annual General Meeting
Annual Report Design by Cowan Graphic Design • www.cowangraphicdesign.com • Photography by David Kennedy, Light's Edge Studios, LLC and Keith Kennedy, Ph.D., TyraTech, Inc.
Advisors
Independent Auditors
Grant Thornton
4140 Parklake Ave.
Suite 130
Raleigh, NC 27612
Legal Counsel
Reed Smith LLP
The Broadgate Tower
20 Primrose Street
London EC2A 2RS
NOTES
1. Attendance and Voting
The Company specifies that only those stockholders registered in the register of members of the Company as at 6.00
p.m. (BST) on 13 July 2012 (or, if the meeting is adjourned, stockholders on the register of members not less than 10 days
before the time fixed for the adjourned meeting) shall be entitled to attend or vote at the above meeting in respect of
the number of shares registered in their name at that time. Changes to entries on the register after 6.00 p.m BST on 13
July 2012 shall be disregarded in determining the rights of any person to attend and vote at the AGM.
2. Proxies
(a) Any member entitled to attend and vote at the AGM is entitled to appoint one or more proxies (who need
not be a member of the Company) to attend and, on a poll, vote instead of the member. Completion and
return of a form of proxy will not preclude a member from attending and voting at the meeting in person,
should he/she subsequently decide to do so.
(b) In order to be valid, any form of proxy, power of attorney or other authority under which it is signed, or
notarially certified office copy of such power or authority, must reach the Company's Registrars, Proxy
Department, Computershare Investor Services (Jersey) Limited at c/o The Pavilions, Bridgwater Road,
Bristol BS99 6ZY or by facsimile at +44 (0)870 703 6109 or by email to externalproxyqueries@computershare.
co.uk not later than 3 p.m. (BST) on 23 July 2012 or in the event of an adjournment 48 hours before the time of
any adjournment of the AGM.
(c) In the case of joint holders, where more than one of the joint holders purports to appoint a proxy, only the
appointment submitted by the most senior holder will be accepted. Seniority is determined by the order
in which the names of the joint holders appear on the Company's register of stockholders in respect of the
joint holding.
(d) If you hold your stock through Depositary Interests please complete a Form of Instruction. This should be
completed and returned to Computershare Investor Services PLC, The Pavilions, Bridgwater Road, Bristol, BS99
6ZY in the enclosed reply paid envelope or by facsimile to +44 (0)870 703 6109 not later than 5 p.m. (BST) on
20 July 2012 or in the event of an adjournment 48 hours before the time of any adjournment of the AGM.
(e) Copies of the letters of appointment of each of the Directors, and the register of Directors' interest in shares
of the Company will be available for inspection at the registered office of the Company during usual business
hours on any weekday (Saturdays, Sundays and public holidays excepted) from the date of this notice until
the date of the AGM and at the place of the AGM from at least 15 minutes prior to and until the conclusion
of the AGM.
If you have any questions on how to complete the Form of Proxy please contact Computershare on telephone number
0870 707 4040 or for questions in relation to the Form of Instruction please contact Computershare on telephone number
0870 703 0027. Calls are charged at local geographic rates. Calls to the helpline from outside of the UK will be charged
at applicable international rates. Different charges may apply to calls from mobile telephones. Please note that calls
to the helpline may be monitored or recorded and that the helpline is not able to advise on the merits of the matters set
out in this document or provide any personal legal, financial or taxation advice.
Nominated Advisor,
Financial Advisor and Broker
N+1 Brewin
12 Smithfield Street
London EC1A 9LA
Registrars
Computershare Investor Services
(Channel Islands) Limited
Queensway House
Hilgrove Street
St. Helier
Jersey, JE1 1ES
